WHAT ARE TOPHI?
Tophi (toe-fye) are rock-like bumps that build up under the skin and around joints. When uric acid levels are high, uric acid can form into crystals that deposit in joints and surrounding tissues. These crystals can build up into larger deposits, eventually forming tophi. Having tophi can be a sign that your uric acid levels are remaining high and that your gout may be progressing.
Where Can Tophi Form on the Body?
Tophi are most frequently found in tissues within and around joints, but they can also pop up in other places, including:
Big Toe
Ears
Elbows
Fingers
Heart
Kidneys
Knees
Nose
Pancreas
Sclera
(Whites of the eyes)
Spine
How Are Tophi Treated?
To effectively treat tophi, you must treat the underlying cause of tophi: uric acid crystal buildup due to high uric acid levels. There are treatments available, including oral and non-oral options, that can help reduce the amount of uric acid in the bloodstream and dissolve the uric acid crystal buildup to help dissolve tophi over time.
Frequently Asked Questions About Tophi and Gout
Can tophi be removed or dissolved?
Yes. Tophi can be removed surgically if they are causing complications, and tophi can also dissolve over time if high uric acid levels are lowered. It's important to note that the surgical removal of tophi does not prevent new tophi from forming. Treating tophi by lowering your uric acid to more normal levels can help break down the uric acid crystals that cause tophi. For women, normal levels of uric acid range between 2.6 mg/dL and 6.0 mg/dL, and for men, a normal range is between 3.5 mg/dL and 7.2 mg/dL.
Can tophi dissolve on their own?
No. Tophi will not go away on their own. Without uric acid reduction to break down uric acid crystal buildup, tophi will not dissolve.
Can tophi impact my overall health? Are tophi dangerous?
Yes. If left untreated, tophi can potentially lead to permanent bone and joint damage. There are also instances when tophi may become infected.